![]() Resistomycin structure
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Common Name | Resistomycin | ||
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CAS Number | 20004-62-0 | Molecular Weight | 376.35900 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C22H16O6 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of ResistomycinResistomycin, a pentacyclic polyketide antibiotic, possesses anticancer activity and induces apoptosis[1][2][3][4]. |
Name | resistomycin |
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Synonym | More Synonyms |
Description | Resistomycin, a pentacyclic polyketide antibiotic, possesses anticancer activity and induces apoptosis[1][2][3][4]. |
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Related Catalog | |
In Vitro | Resistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation[1]. Resistomycin displays a high affinity for GST-Pellino-1 (KD = 2.58 μM) as indicated by surface plasmon resonance[1]. Resistomycin treatment reduced the expression of SNAIL and SLUG in TNBC cells[1]. Resistomycin induced apoptosis and cycle arrest in human hepatocellular carcinoma cells by activating p38 MAPK pathway in vitro and in vivo[3]. |
Molecular Formula | C22H16O6 |
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Molecular Weight | 376.35900 |
Exact Mass | 376.09500 |
PSA | 115.06000 |
LogP | 3.65590 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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HS Code | 2914400090 |
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~87% Resistomycin CAS#:20004-62-0 |
Literature: Kelly; Ghoshal Journal of the American Chemical Society, 1985 , vol. 107, # 13 p. 3879 - 3884 |
~% Resistomycin CAS#:20004-62-0 |
Literature: Kelly; Ghoshal Journal of the American Chemical Society, 1985 , vol. 107, # 13 p. 3879 - 3884 |
~% Resistomycin CAS#:20004-62-0 |
Literature: Kelly; Ghoshal Journal of the American Chemical Society, 1985 , vol. 107, # 13 p. 3879 - 3884 |
~% Resistomycin CAS#:20004-62-0 |
Literature: Kelly; Ghoshal Journal of the American Chemical Society, 1985 , vol. 107, # 13 p. 3879 - 3884 |
HS Code | 2914400090 |
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Summary | 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-2H-benzo[cd]pyrene-2,6(1H)-dione |
A 3733A |
Itamycin |
3,5,7,10-tetrahydroxy-1,1,9-trimethyl-1H-benzo[cd]pyrene-2,6-dione |
2H-Benzo(cd)pyrene-2,6(1H)-dione,3,5,7,10-tetrahydroxy-1,1,9-trimethyl |
Geliomycin |
Antibiotic A 3733a |
3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-1H-benzo[cd]pyren-2,6-dion |
Croceomycin |