3-CPs
Modify Date: 2024-01-10 11:59:23
3-CPs structure
|
Common Name | 3-CPs | ||
|---|---|---|---|---|
| CAS Number | 20073-24-9 | Molecular Weight | 258.22600 | |
| Density | 1.387g/cm3 | Boiling Point | 437.3ºC at 760 mmHg | |
| Molecular Formula | C14H10O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 218.3ºC | |
Use of 3-CPs3-CPs is a serotype capsular polysaccharide which can interfere with antibody-mediated bacterial killing. |
| Name | 3-(ethoxycarbonyl)psoralen |
|---|---|
| Synonym | More Synonyms |
| Description | 3-CPs is a serotype capsular polysaccharide which can interfere with antibody-mediated bacterial killing. |
|---|---|
| Related Catalog | |
| In Vitro | 3-CPs displays protective effect against UVB damage in all concentrations tested[1]. About 50% inhibition of bacterial killing is observed when 12 ng of purified type 3 CPS is added to the OPKA. The addition of 30 μL of mouse serum post-i.p. infection with WU2 (containing 0.4 to 0.7 μg/mL released type 3 CPS) shows 26% to 52% inhibition of bacterial killing, comparable to what is observed when an equivalent amount of purified CPS is added[2]. |
| Kinase Assay | To measure the inhibitory effect of releaseing type 3-CPs on bacteria killing, an OPKA is performed with the addition of culture supernatant or mouse serum obtained at 24 h following i.p. injection with 103 CFU of the S. pneumoniae WU2 strain. In each well, 10 μL of diluted rabbit serum is mixed with 10 μL of strain WU2 (1,000 CFU) and 10 μL of culture supernatant or mouse serum for 30 min at room temperature before HL-60 cells and complement are added. The percent inhibition of bacterial killing is compared to that with the OPKA with the addition of ΔCPS WU2 culture supernatant or naive mouse serum containing no 3-CPs[2]. |
| References |
| Density | 1.387g/cm3 |
|---|---|
| Boiling Point | 437.3ºC at 760 mmHg |
| Molecular Formula | C14H10O5 |
| Molecular Weight | 258.22600 |
| Flash Point | 218.3ºC |
| Exact Mass | 258.05300 |
| PSA | 69.65000 |
| LogP | 2.71590 |
| Vapour Pressure | 7.54E-08mmHg at 25°C |
| Index of Refraction | 1.621 |
| Storage condition | 2-8℃ |
| HS Code | 2932999099 |
|---|
|
~%
3-CPs CAS#:20073-24-9 |
| Literature: Horning; Reisner Journal of the American Chemical Society, 1950 , vol. 72, p. 1514,1516 |
![ethyl 7-oxo-2,3-dihydrofuro[3,2-g]chromene-6-carboxylate structure](https://image.chemsrc.com/caspic/113/73097-13-9.png)
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| ethyl 7-oxofuro[3,2-g]chromene-6-carboxylate |
| 7-oxo-7H-furo[3,2-g]chromene-6-carboxylic acid ethyl ester |
| EINECS 243-498-7 |
| 7H-Furo(3,2-g)(1)benzopyran-6-carboxylic acid,7-oxo-,ethyl ester |
| 3-carbethoxysporalen |
| 3-carbethoxy psoralene |
| 7-Oxo-7H-furo[3,2-g]chromen-6-carbonsaeure-aethylester |
| 3-CPs |
| ethyl 7-oxo-7H-furo[3,2-g][1]benzopyran-6-carboxylate |
| 3-Ethoxycarbonylpsoralen |
| 7-Oxo-7H-furo(3,2-g)(1)benzopyran-6-carboxylic acid ethyl ester |
| 3-ethoxycarbonylfurocoumarin |
| 3-CARBETHOXYPSORALEN |
| Ethyl 3-psoralencarboxylate |