VH032-NH-CO-CH2-NHBoc

Modify Date: 2024-01-29 11:29:28

VH032-NH-CO-CH2-NHBoc Structure
VH032-NH-CO-CH2-NHBoc structure
Common Name VH032-NH-CO-CH2-NHBoc
CAS Number 2010986-19-1 Molecular Weight 587.73
Density N/A Boiling Point N/A
Molecular Formula C29H41N5O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VH032-NH-CO-CH2-NHBoc


VH032-NH-CO-CH2-NHBoc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL to recruit von Hippel-Lindau (VHL) proteins. VH032-NH-CO-CH2-NHBoc will remove the Boc protection under acidic conditions, and connect with the target protein ligand through a linker to form a PROTAC molecule, which is a key intermediate for the synthesis of PROTAC based on VHL ligand.

 Names

Name L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]glycyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

 VH032-NH-CO-CH2-NHBoc Biological Activity

Description VH032-NH-CO-CH2-NHBoc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL to recruit von Hippel-Lindau (VHL) proteins. VH032-NH-CO-CH2-NHBoc will remove the Boc protection under acidic conditions, and connect with the target protein ligand through a linker to form a PROTAC molecule, which is a key intermediate for the synthesis of PROTAC based on VHL ligand.
Related Catalog

 Chemical & Physical Properties

Molecular Formula C29H41N5O6S
Molecular Weight 587.73