HER2-IN-2
Modify Date: 2024-07-24 18:41:26
HER2-IN-2 structure
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Common Name | HER2-IN-2 | ||
|---|---|---|---|---|
| CAS Number | 2011708-43-1 | Molecular Weight | 373.372 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H15N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HER2-IN-2HER2-IN-2 is a potent, selective HER2 inhibitor, only shows potent inhibition for EGFR and Abl in a panel of kinases; equipotent to lapatinib against HER2 in vitro, also able to inhibit the small amount of HER3 auto-phosphorylation; inhibits 2YF/3TM gatekeeper mutant Ba/F3 cells lines with IC50 of 18.63 nM. |
| Name | HER2-IN-2 |
|---|
| Description | HER2-IN-2 is a potent, selective HER2 inhibitor, only shows potent inhibition for EGFR and Abl in a panel of kinases; equipotent to lapatinib against HER2 in vitro, also able to inhibit the small amount of HER3 auto-phosphorylation; inhibits 2YF/3TM gatekeeper mutant Ba/F3 cells lines with IC50 of 18.63 nM. |
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| References | References 1. Novotny CJ, et al. Nat Chem Biol. 2016 Nov;12(11):923-930. View Related Products by Target EGFR |
| Molecular Formula | C20H15N5O3 |
|---|---|
| Molecular Weight | 373.372 |