HER2-IN-3
Modify Date: 2024-04-05 19:36:14
HER2-IN-3 structure
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Common Name | HER2-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2011708-45-3 | Molecular Weight | 372.388 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H16N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HER2-IN-3HER2-IN-3 is a type I HER2 inhibitor that has a similar profile to HER2-IN-2; shows superior activity to lapatinib in the 2YF/3wt + NRG cells and specificity for this cell line; remains sensitivity to HER2 mutations L755S (2YF-L755S/3wt), Y772_A775 dup (2YF-YVMA/3wt), and G776del_insVC (2YF-VC/3wt) cells. |
| Name | HER2-IN-3 |
|---|
| Description | HER2-IN-3 is a type I HER2 inhibitor that has a similar profile to HER2-IN-2; shows superior activity to lapatinib in the 2YF/3wt + NRG cells and specificity for this cell line; remains sensitivity to HER2 mutations L755S (2YF-L755S/3wt), Y772_A775 dup (2YF-YVMA/3wt), and G776del_insVC (2YF-VC/3wt) cells. |
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| References | References 1. Novotny CJ, et al. Nat Chem Biol. 2016 Nov;12(11):923-930. View Related Products by Target EGFR |
| Molecular Formula | C20H16N6O2 |
|---|---|
| Molecular Weight | 372.388 |