USP8-IN-3
Modify Date: 2024-01-17 23:02:36
USP8-IN-3 structure
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Common Name | USP8-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2477651-10-6 | Molecular Weight | 425.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H18F3N5O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of USP8-IN-3USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively[1]. |
| Name | USP8-IN-3 |
|---|
| Description | USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively[1]. |
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| Related Catalog | |
| Target |
USP8:4.0 μM (IC50) |
| In Vitro | USP8-IN-3 (6.25-100 μM; 15 min) 抑制 USP8 对二聚泛素的剪切活性[1]。 Western Blot Analysis[1] Cell Line: / Concentration: 6.25 μM, 12.5 μM, 25 μM, 50 μM, and 100 μM Incubation Time: 15 min; added Di-Ub substrate for another 1 h Result: Decreased the cleaved diubiquitin level. |
| References |
| Molecular Formula | C18H18F3N5O2S |
|---|---|
| Molecular Weight | 425.43 |