CD80-IN-3

Modify Date: 2024-01-19 21:12:26

CD80-IN-3 Structure
CD80-IN-3 structure
Common Name CD80-IN-3
CAS Number 486449-65-4 Molecular Weight 323.27800
Density 1.536g/cm3 Boiling Point 594.3ºC at 760 mmHg
Molecular Formula C17H10FN3O3 Melting Point N/A
MSDS N/A Flash Point 313.2ºC

 Use of CD80-IN-3


CD80-IN-3, a potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM.

 Names

Name 4-(6-fluoro-3-oxo-1H-pyrazolo[4,3-c]quinolin-2-yl)benzoic acid

 CD80-IN-3 Biological Activity

Description CD80-IN-3, a potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM.
Related Catalog
References

[1]. Huxley P, et al. High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy. Chem Biol. 2004 Dec;11(12):1651-8.

 Chemical & Physical Properties

Density 1.536g/cm3
Boiling Point 594.3ºC at 760 mmHg
Molecular Formula C17H10FN3O3
Molecular Weight 323.27800
Flash Point 313.2ºC
Exact Mass 323.07100
PSA 87.98000
LogP 2.70430
Index of Refraction 1.725