DHODH-IN-3 structure
|
Common Name | DHODH-IN-3 | ||
---|---|---|---|---|
CAS Number | 1148126-04-8 | Molecular Weight | 312.75 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C17H13ClN2O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of DHODH-IN-3DHODH-IN-3 (compound 3) is a potent inhibitor of Human Dihydroorotate Dehydrogenases (HsDHODH) with an IC50 value of 261 nM. DHODH-IN-3 binds to the the ubiquinone binding cavities in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential for malaria treatment[1]. |
Name | DHODH-IN-3 |
---|
Description | DHODH-IN-3 (compound 3) is a potent inhibitor of Human Dihydroorotate Dehydrogenases (HsDHODH) with an IC50 value of 261 nM. DHODH-IN-3 binds to the the ubiquinone binding cavities in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential for malaria treatment[1]. |
---|---|
Related Catalog | |
Target |
IC50: 261 nM (HsDHODH)[1] |
In Vitro | DHODH-IN-3 (compound 3) show good inhibitory effects on HsDHODH with IC50 value of 261 nM. It binds to HsDHODH with a Kiapp value of 32 nM[1]. |
References |
Molecular Formula | C17H13ClN2O2 |
---|---|
Molecular Weight | 312.75 |