2029049-77-0
2029049-77-0 structure
- Name: DHODH-IN-7
- Chemical Name: DHODH-IN-7
- CAS Number: 2029049-77-0
- Molecular Formula: C21H21F3N2O2
- Molecular Weight: 390.40
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
- Create Date: 2020-04-04 23:09:32
- Modify Date: 2024-01-10 12:38:32
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DHODH-IN-7 is a human dihydroorotate dehydrogenase (DHODH) inhibitor, with an IC50 of 0.91 μM. DHODH-IN-7 induces differentiation in acute myeloid leukemia[1].
| Name | DHODH-IN-7 |
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| Description | DHODH-IN-7 is a human dihydroorotate dehydrogenase (DHODH) inhibitor, with an IC50 of 0.91 μM. DHODH-IN-7 induces differentiation in acute myeloid leukemia[1]. |
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| Related Catalog | |
| In Vitro | The lysozyme-GFPER-HoxA9 murine cell line (ER-HOX-GFP) and the THP1 and U937 human AML cell lines were cultured with compounds in a 4-day differentiation assay. DHODH-IN-7 shows EC50s of 3.6, 2.7, and 2.5 μM for ER-HOX-GFP, THP1 and U937 human AML cell lines, respectively[1]. |
| References |
| Molecular Formula | C21H21F3N2O2 |
|---|---|
| Molecular Weight | 390.40 |
| Hazard Codes | Xi |
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