Rutundic acid

Modify Date: 2024-01-06 10:40:03

Rutundic acid structure	Common Name	Rutundic acid
	CAS Number	20137-37-5	Molecular Weight	488.699
	Density	1.2±0.1 g/cm3	Boiling Point	622.8±55.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₄₈O₅	Melting Point	272-274℃
	MSDS	N/A	Flash Point	344.5±28.0 °C

Use of Rutundic acid

Rotundic acid, a triterpenoid obtained from I. rotunda, induces DNA damage and cell apoptosis in hepatocellular carcinoma through AKT/mTOR and MAPK Pathways. Rotundic acid possesses anti-inflammatory and cardio-protective abilities[1].

Name	(1R,2R,4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-1,10-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
Synonym	More Synonyms

Description	Rotundic acid, a triterpenoid obtained from I. rotunda, induces DNA damage and cell apoptosis in hepatocellular carcinoma through AKT/mTOR and MAPK Pathways. Rotundic acid possesses anti-inflammatory and cardio-protective abilities[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> Akt
Target	Akt mTOR p38 MAPK
References	[1]. Roy G, et al. Rotundic Acid Induces DNA Damage and Cell Death in Hepatocellular Carcinoma Through AKT/mTOR and MAPK Pathways. Front Oncol. 2019 Jun 26;9:545.

Density	1.2±0.1 g/cm3
Boiling Point	622.8±55.0 °C at 760 mmHg
Melting Point	272-274℃
Molecular Formula	C₃₀H₄₈O₅
Molecular Weight	488.699
Flash Point	344.5±28.0 °C
Exact Mass	488.350189
PSA	97.99000
LogP	5.75
Vapour Pressure	0.0±4.1 mmHg at 25°C
Index of Refraction	1.581
Storage condition	-20℃