Desthiobiotin-PEG4-DBCO

Modify Date: 2024-01-08 16:28:37

Desthiobiotin-PEG4-DBCO Structure
Desthiobiotin-PEG4-DBCO structure
Common Name Desthiobiotin-PEG4-DBCO
CAS Number 2032788-37-5 Molecular Weight 719.87
Density N/A Boiling Point N/A
Molecular Formula C39H53N5O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Desthiobiotin-PEG4-DBCO


DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG4-Desthiobiotin

 Desthiobiotin-PEG4-DBCO Biological Activity

Description DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C39H53N5O8
Molecular Weight 719.87
Storage condition -20°C