RTI 4229-336
Modify Date: 2024-03-02 22:02:18
RTI 4229-336 structure
|
Common Name | RTI 4229-336 | ||
|---|---|---|---|---|
| CAS Number | 204069-50-1 | Molecular Weight | 429.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H26Cl2N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RTI 4229-336RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels[1]. |
| Name | RTI-336 |
|---|---|
| Synonym | More Synonyms |
| Description | RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels[1]. |
|---|---|
| Related Catalog | |
| In Vivo | RTI 336（3 mg/kg；皮下注射；30 分钟预处理）显著减少 Lewis 大鼠对成瘾剂的输注次数[1]。 RTI 336（3 毫克/千克；腹腔注射；30 分钟预处理）降低 Lewis 大鼠中由成瘾剂诱导的反应率（杠杆按压/秒）[1]。 |
| References |
| Molecular Formula | C24H26Cl2N2O |
|---|---|
| Molecular Weight | 429.38 |
| Exact Mass | 428.142212 |
| (1R,2S,3S,5S)-3-(4-Chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-1,2-oxazol-5-yl]-8-azabicyclo[3.2.1]octane hydrochloride (1:1) |
| 8-Azabicyclo[3.2.1]octane, 3-(4-chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-5-isoxazolyl]-, (1R,2S,3S,5S)-, hydrochloride (1:1) |
| RTI-336 |