Aminooxy-PEG8-methane HCl

Modify Date: 2024-01-09 14:21:08

Aminooxy-PEG8-methane HCl Structure
Aminooxy-PEG8-methane HCl structure
Common Name Aminooxy-PEG8-methane HCl
CAS Number 2055024-52-5 Molecular Weight 399.48
Density N/A Boiling Point N/A
Molecular Formula C17H37NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aminooxy-PEG8-methane HCl


Aminooxy-PEG8-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Aminooxy-PEG8-methane
Synonym More Synonyms

 Aminooxy-PEG8-methane HCl Biological Activity

Description Aminooxy-PEG8-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H37NO9
Molecular Weight 399.48

 Synonyms

MFCD29918216
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