MC-Val-Cit-PAB-duocarmycin

Modify Date: 2024-01-10 08:43:34

MC-Val-Cit-PAB-duocarmycin Structure
MC-Val-Cit-PAB-duocarmycin structure
Common Name MC-Val-Cit-PAB-duocarmycin
CAS Number 2055896-98-3 Molecular Weight 1019.60
Density N/A Boiling Point N/A
Molecular Formula C54H65ClN9O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-Val-Cit-PAB-duocarmycin


MC-Val-Cit-PAB-duocarmycin has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-duocarmycin is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].

 Names

Name MC-Val-Cit-PAB-duocarmycin

 MC-Val-Cit-PAB-duocarmycin Biological Activity

Description MC-Val-Cit-PAB-duocarmycin has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-duocarmycin is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].
Related Catalog
References

[1]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

 Chemical & Physical Properties

Molecular Formula C54H65ClN9O9
Molecular Weight 1019.60