SL-651,498

Modify Date: 2024-03-10 19:38:05

SL-651,498 Structure
SL-651,498 structure
Common Name SL-651,498
CAS Number 205881-86-3 Molecular Weight 389.42200
Density N/A Boiling Point N/A
Molecular Formula C23H20FN3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SL-651,498


SL651498 is a full agonist of α2 and α3 GABAA receptors, and a partial agonist of α1 and α5 GABAA receptors. SL651498 shows anxiolytic and anticonvulsant activities[1].

 Names

Name 6-Fluoro-9-methyl-2-phenyl-4-(1-pyrrolidinylcarbonyl)-2,9-dihydro -1H-β-carbolin-1-one

 SL-651,498 Biological Activity

Description SL651498 is a full agonist of α2 and α3 GABAA receptors, and a partial agonist of α1 and α5 GABAA receptors. SL651498 shows anxiolytic and anticonvulsant activities[1].
Related Catalog
References

[1]. G Griebel, et al. SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors. J Pharmacol Exp Ther. 2001 Aug;298(2):753-68.  

 Chemical & Physical Properties

Molecular Formula C23H20FN3O2
Molecular Weight 389.42200
Exact Mass 389.15400
PSA 47.24000
LogP 3.79540
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