N,N'-DME-N,N'-Bis-PEG2-acid

Modify Date: 2024-01-09 19:09:18

N,N'-DME-N,N'-Bis-PEG2-acid Structure
N,N'-DME-N,N'-Bis-PEG2-acid structure
Common Name N,N'-DME-N,N'-Bis-PEG2-acid
CAS Number 2062663-61-8 Molecular Weight 408.49
Density N/A Boiling Point N/A
Molecular Formula C18H36N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N,N'-DME-N,N'-Bis-PEG2-acid


N,N'-DME-N,N'-Bis-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N,N'-DME-N,N'-Bis-PEG2-acid

 N,N'-DME-N,N'-Bis-PEG2-acid Biological Activity

Description N,N'-DME-N,N'-Bis-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H36N2O8
Molecular Weight 408.49
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