(S)-C33

Modify Date: 2024-07-27 18:05:59

(S)-C33 Structure
(S)-C33 structure
Common Name (S)-C33
CAS Number 2066488-39-7 Molecular Weight 357.837
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H20ClN5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-C33


A novel potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms; shows better selectivity than (R)-C33 against PDE5.

 Names

Name 6-{[(1S)-1-(4-Chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
Synonym More Synonyms

 (S)-C33 Biological Activity

Description A novel potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms; shows better selectivity than (R)-C33 against PDE5.
References References 1. Huang M, et al. Mol Pharmacol. 2015 Nov;88(5):836-45. View Related Products by Target Phosphodiesterase (PDE)

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C18H20ClN5O
Molecular Weight 357.837
Exact Mass 357.135651
LogP 2.70
Index of Refraction 1.725
Storage condition -20°C

 Synonyms

6-{[(1S)-1-(4-Chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[[(1S)-1-(4-chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-
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