2066488-39-7
2066488-39-7 structure
- Name: (S)-C33
- Chemical Name: 6-{[(1S)-1-(4-Chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
- CAS Number: 2066488-39-7
- Molecular Formula: C18H20ClN5O
- Molecular Weight: 357.837
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
- Create Date: 2020-01-11 13:52:30
- Modify Date: 2024-07-27 18:05:59
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A novel potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms; shows better selectivity than (R)-C33 against PDE5.
| Name | 6-{[(1S)-1-(4-Chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one |
|---|---|
| Synonyms |
6-{[(1S)-1-(4-Chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[[(1S)-1-(4-chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro- |
| Description | A novel potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms; shows better selectivity than (R)-C33 against PDE5. |
|---|---|
| References | References 1. Huang M, et al. Mol Pharmacol. 2015 Nov;88(5):836-45. View Related Products by Target Phosphodiesterase (PDE) |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C18H20ClN5O |
| Molecular Weight | 357.837 |
| Exact Mass | 357.135651 |
| LogP | 2.70 |
| Index of Refraction | 1.725 |
| Storage condition | -20°C |