2066488-39-7

2066488-39-7 structure

Name: (S)-C33
Chemical Name: 6-{[(1S)-1-(4-Chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
CAS Number: 2066488-39-7
Molecular Formula: C₁₈H₂₀ClN₅O
Molecular Weight: 357.837
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2020-01-11 13:52:30
Modify Date: 2024-07-27 18:05:59
A novel potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms; shows better selectivity than (R)-C33 against PDE5.

Name	6-{[(1S)-1-(4-Chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
Synonyms	6-{[(1S)-1-(4-Chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[[(1S)-1-(4-chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-

Description	A novel potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms; shows better selectivity than (R)-C33 against PDE5.
References	References 1. Huang M, et al. Mol Pharmacol. 2015 Nov;88(5):836-45. View Related Products by Target Phosphodiesterase (PDE)