3-Bromocytisine

Modify Date: 2024-01-09 00:32:59

3-Bromocytisine structure	Common Name	3-Bromocytisine
	CAS Number	207390-14-5	Molecular Weight	269.13800
	Density	1.61±0.1 g/cm3(Predicted)	Boiling Point	463.3±45.0 °C(Predicted)
	Molecular Formula	C₁₁H₁₃BrN₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3-Bromocytisine

3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively[1][2].

Name	(1R,9S)-5-Bromo-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one

Description	3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
Target	IC50: 0.28 nM (hα4β4), 0.30 nM (hα4β2), 31.6 nM (hα7)[1]
References	[1]. Houlihan LM, et al. Activity of cytisine and its brominated isosteres on recombinant human alpha7, alpha4beta2 and alpha4beta4 nicotinic acetylcholine receptors. J Neurochem. 2001 Sep;78(5):1029-43. [2]. Moroni M, et al. alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine. Mol Pharmacol. 2006 Aug;70(2):755-68.

Density	1.61±0.1 g/cm3(Predicted)
Boiling Point	463.3±45.0 °C(Predicted)
Molecular Formula	C₁₁H₁₃BrN₂O
Molecular Weight	269.13800
Exact Mass	268.02100
PSA	34.03000
LogP	1.64630
Storage condition	2-8°C

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 3-Bromocytisine
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: 3-Bromocytisine
Price: $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: 3-Bromocytisine
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-Bromocytisine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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