3-Bromocytisine
Modify Date: 2024-01-09 00:32:59
3-Bromocytisine structure
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Common Name | 3-Bromocytisine | ||
|---|---|---|---|---|
| CAS Number | 207390-14-5 | Molecular Weight | 269.13800 | |
| Density | 1.61±0.1 g/cm3(Predicted) | Boiling Point | 463.3±45.0 °C(Predicted) | |
| Molecular Formula | C11H13BrN2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3-Bromocytisine3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively[1][2]. |
| Name | (1R,9S)-5-Bromo-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one |
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| Description | 3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively[1][2]. |
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| Related Catalog | |
| Target |
IC50: 0.28 nM (hα4β4), 0.30 nM (hα4β2), 31.6 nM (hα7)[1] |
| References |
| Density | 1.61±0.1 g/cm3(Predicted) |
|---|---|
| Boiling Point | 463.3±45.0 °C(Predicted) |
| Molecular Formula | C11H13BrN2O |
| Molecular Weight | 269.13800 |
| Exact Mass | 268.02100 |
| PSA | 34.03000 |
| LogP | 1.64630 |
| Storage condition | 2-8°C |