RS-601
Modify Date: 2024-01-10 20:34:25
RS-601 structure
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Common Name | RS-601 | ||
|---|---|---|---|---|
| CAS Number | 207987-59-5 | Molecular Weight | 511.478 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 563.3±60.0 °C at 760 mmHg | |
| Molecular Formula | C22H23F6NO4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 294.5±32.9 °C | |
Use of RS-601RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities. |
| Name | RS-601 |
|---|---|
| Synonym | More Synonyms |
| Description | RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities. |
|---|---|
| Related Catalog | |
| Target |
LTD4 TXA2 Receptor |
| In Vivo | RS-601 (1-10 mg/kg) clearly inhibits the bronchoconstriction induced by intravenous administration of U-46619 and LTD4 in a dose-dependent fashion in guinea pigs. RS-1452 (10 mg/kg) significantly inhibits U-46619-induced bronchoconstriction, respectively. RS-601 significantly inhibits the late-phase response and LPS-induced AHR at a dose of 10 mg/kg, but does not affect biphasic bronchial responses. RS-601 (3 and 10 mg/kg) also clearly inhibits the AHR[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 563.3±60.0 °C at 760 mmHg |
| Molecular Formula | C22H23F6NO4S |
| Molecular Weight | 511.478 |
| Flash Point | 294.5±32.9 °C |
| Exact Mass | 511.125183 |
| LogP | 4.84 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.511 |
| Storage condition | 2-8℃ |
| 4-[4-(5,5,6,6,6-Pentafluoro-1-{[(4-fluorophenyl)sulfonyl]amino}hexyl)phenyl]butanoic acid |
| 4-(4-(5,5,6,6,6-pentafluoro-1-(4-fluorobenzene-sulfonamido)hexyl)phenyl)butyric acid |
| Benzenebutanoic acid, 4-[5,5,6,6,6-pentafluoro-1-[[(4-fluorophenyl)sulfonyl]amino]hexyl]- |