BI-8668 structure
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Common Name | BI-8668 | ||
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CAS Number | 2084059-97-0 | Molecular Weight | 523.463 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C23H32Cl2N8O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of BI-8668BI-8668 (BI 8668) is a highly potent and selective epithelial sodium channel (ENaC) inhibitor, inhibits Na+ current with IC50 of 17 nM (Ussing chamber assay);BI-8668 inhibits ENaC-mediated water permeability through cell monolayers of the cell line M-1 (M-1 cells: mouse kidney tubules cells) with 81% inhibition at 3 uM. |
Name | BI-8668 |
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Description | BI-8668 (BI 8668) is a highly potent and selective epithelial sodium channel (ENaC) inhibitor, inhibits Na+ current with IC50 of 17 nM (Ussing chamber assay);BI-8668 inhibits ENaC-mediated water permeability through cell monolayers of the cell line M-1 (M-1 cells: mouse kidney tubules cells) with 81% inhibition at 3 uM. |
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Molecular Formula | C23H32Cl2N8O2 |
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Molecular Weight | 523.463 |