2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane

Modify Date: 2024-01-02 13:12:16

2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane Structure
2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane structure
Common Name 2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane
CAS Number 2086689-02-1 Molecular Weight 461.53
Density N/A Boiling Point N/A
Molecular Formula C19H31N3O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane


2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid)
Synonym More Synonyms

  Biological Activity

Description 2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H31N3O8S
Molecular Weight 461.53

 Synonyms

MFCD30723274
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