Acid-PEG1-C2-Boc

Modify Date: 2024-01-31 16:29:03

Acid-PEG1-C2-Boc Structure
Acid-PEG1-C2-Boc structure
Common Name Acid-PEG1-C2-Boc
CAS Number 2086689-08-7 Molecular Weight 218.25
Density N/A Boiling Point N/A
Molecular Formula C10H18O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Acid-PEG1-C2-Boc


Acid-PEG1-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Acid-PEG1-t-butyl ester
Synonym More Synonyms

 Acid-PEG1-C2-Boc Biological Activity

Description Acid-PEG1-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H18O5
Molecular Weight 218.25

 Synonyms

MFCD30723273
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