HSL-IN-1

Modify Date: 2024-01-14 15:48:49

HSL-IN-1 Structure
HSL-IN-1 structure
Common Name HSL-IN-1
CAS Number 2095156-13-9 Molecular Weight 436.58
Density N/A Boiling Point N/A
Molecular Formula C19H13BClF3N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HSL-IN-1


HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1].

 Names

Name HSL-IN-1

 HSL-IN-1 Biological Activity

Description HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1].
Related Catalog
Target

IC50: 2 nM (Hormone sensitive lipase)[1]

References

[1]. Ogiyama T, et al. Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation. Bioorg Med Chem. 2017 Apr 1;25(7):2234-2243.

 Chemical & Physical Properties

Molecular Formula C19H13BClF3N2O4
Molecular Weight 436.58