IACS-8803

Modify Date: 2024-04-06 12:33:49

IACS-8803 Structure
IACS-8803 structure
Common Name IACS-8803
CAS Number 2095690-70-1 Molecular Weight 692.53
Density N/A Boiling Point N/A
Molecular Formula C20H23FN10O9P2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IACS-8803


IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy[1].

 Names

Name IACS-8803

 IACS-8803 Biological Activity

Description IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy[1].
Related Catalog
Target

STING[1]

In Vivo IACS-8803 shows a superior systemic anti-tumor response in the B16 murine model of melanoma[1].
References

[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.

 Chemical & Physical Properties

Molecular Formula C20H23FN10O9P2S2
Molecular Weight 692.53