Isotanshinone IIA

Modify Date: 2024-01-05 18:46:57

Isotanshinone IIA Structure
Isotanshinone IIA structure
Common Name Isotanshinone IIA
CAS Number 20958-15-0 Molecular Weight 294.34400
Density N/A Boiling Point 471.1±45.0 °C(Predicted)
Molecular Formula C19H18O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Isotanshinone IIA


Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.

 Names

Name isotanshinone IIA
Synonym More Synonyms

 Isotanshinone IIA Biological Activity

Description Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.
Related Catalog
Target

IC50: 11.4 μM (PTP1B)[1].

References

[1]. Han YM, et al. PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza. Biol Pharm Bull. 2005 Sep;28(9):1795-7.

 Chemical & Physical Properties

Boiling Point 471.1±45.0 °C(Predicted)
Molecular Formula C19H18O3
Molecular Weight 294.34400
Exact Mass 294.12600
PSA 47.28000
LogP 3.97730

 Safety Information

Hazard Codes Xi

 Synonyms

4,4,8-Trimethyl-2,3-dihydro-1H,4H-10-oxa-cyclopenta[b]phenanthrene-7,11-dione
Isotanshinon-II
isotanshinone II
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