para-amino-Blebbistatin

Modify Date: 2024-01-14 14:09:38

para-amino-Blebbistatin Structure
para-amino-Blebbistatin structure
Common Name para-amino-Blebbistatin
CAS Number 2097734-03-5 Molecular Weight 307.346
Density 1.4±0.1 g/cm3 Boiling Point 571.3±60.0 °C at 760 mmHg
Molecular Formula C18H17N3O2 Melting Point N/A
MSDS N/A Flash Point 299.3±32.9 °C

 Use of para-amino-Blebbistatin


Para-aminoblebbistatin is a highly water soluble, non-fluorescent and photostable C15 amino-substituted derivative of blebbistatin; inhibits various (myosin II) isoforms both in vitro and in vivo.

 Names

Name para-amino-Blebbistatin
Synonym More Synonyms

 para-amino-Blebbistatin Biological Activity

Description Para-aminoblebbistatin is a highly water soluble, non-fluorescent and photostable C15 amino-substituted derivative of blebbistatin; inhibits various (myosin II) isoforms both in vitro and in vivo.
Related Catalog
Target

Myosin II[1]

References

[1]. Várkuti BH, et al. A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative. Sci Rep. 2016 May 31;6:26141.  

[2]. Képiró M, et al. para-Nitroblebbistatin, the non-cytotoxic and photostable myosin II inhibitor. Angew Chem Int Ed Engl. 2014 Jul 28;53(31):8211-5.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 571.3±60.0 °C at 760 mmHg
Molecular Formula C18H17N3O2
Molecular Weight 307.346
Flash Point 299.3±32.9 °C
Exact Mass 307.132080
LogP 0.34
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.715
Storage condition 2-8°C

 Synonyms

(3aS)-1-(4-Aminophenyl)-3a-hydroxy-6-methyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
4H-Pyrrolo[2,3-b]quinolin-4-one, 1-(4-aminophenyl)-1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-, (3aS)-
para-amino-Blebbistatin
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