AT-121 hydrochloride

Modify Date: 2024-01-03 11:52:03

AT-121 hydrochloride structure	Common Name	AT-121 hydrochloride
	CAS Number	2099681-71-5	Molecular Weight	499.11
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₃₉ClN₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AT-121 hydrochloride

AT-121 hydrochloride is a bifunctional nociception and mu opioid receptor agonist, with Kis of 3.67 and 16.49 nM, respectively. AT-121 hydrochloride is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects[1].

Name	AT-121 hydrochloride

Description	AT-121 hydrochloride is a bifunctional nociception and mu opioid receptor agonist, with Kis of 3.67 and 16.49 nM, respectively. AT-121 hydrochloride is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
In Vivo	AT-121 hydrochloride (0.003-0.03 mg/kg; s.c.) produces potent antinociceptive effect[1]. Animal Model: Adult male and female rhesus monkeys[1] Dosage: 0.003-0.03 mg/kg Administration: Subcutaneous Result: Produced antinociceptive effects against an acute noxious stimulus, 50 °C water, in a dose-dependent.
References	[1]. Ding H, et al. A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates. Sci Transl Med. 2018;10(456):eaar3483.

Molecular Formula	C₂₄H₃₉ClN₄O₃S
Molecular Weight	499.11

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AT-121 hydrochloride
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Purity: 98.0%
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