N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride)

Modify Date: 2024-01-09 22:13:32

N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride) Structure
N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride) structure
Common Name N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride)
CAS Number 2107273-04-9 Molecular Weight 619.23
Density N/A Boiling Point N/A
Molecular Formula C37H47ClN2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride)


N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-methyl-N'-(propargyl-PEG4)-Cy5

  Biological Activity

Description N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C37H47ClN2O4
Molecular Weight 619.23