Flumethasone
Flumethasone structure
|
Common Name | Flumethasone | ||
|---|---|---|---|---|
| CAS Number | 2135-17-3 | Molecular Weight | 410.452 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 569.8±50.0 °C at 760 mmHg | |
| Molecular Formula | C22H28F2O5 | Melting Point | 237-240ºC | |
| MSDS | Chinese USA | Flash Point | 298.4±30.1 °C | |
| Symbol |
GHS08 |
Signal Word | Warning | |
Use of FlumethasoneFlumethasone is a corticosteroid for topical use, in combination with Clioquinol for the treatment of otitis externa and otomycosis. Flumethasone shows fully 420 times the potency of cortisone in an animal model for anti-inflammatory activity. |
| Name | flumethasone |
|---|---|
| Synonym | More Synonyms |
| Description | Flumethasone is a corticosteroid for topical use, in combination with Clioquinol for the treatment of otitis externa and otomycosis. Flumethasone shows fully 420 times the potency of cortisone in an animal model for anti-inflammatory activity. |
|---|---|
| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 569.8±50.0 °C at 760 mmHg |
| Melting Point | 237-240ºC |
| Molecular Formula | C22H28F2O5 |
| Molecular Weight | 410.452 |
| Flash Point | 298.4±30.1 °C |
| Exact Mass | 410.190491 |
| PSA | 94.83000 |
| LogP | 1.61 |
| Vapour Pressure | 0.0±3.6 mmHg at 25°C |
| Index of Refraction | 1.579 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H351 |
| Precautionary Statements | P281 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R40 |
| Safety Phrases | S22-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | TU3832000 |
| HS Code | 2937229000 |
|
~%
Flumethasone CAS#:2135-17-3 |
| Literature: WO2012/11106 A1, ; Page/Page column 20 ; |
|
~%
Flumethasone CAS#:2135-17-3 |
| Literature: Farmaco, , vol. 51, # 12 p. 809 - 810 |
|
~%
Flumethasone CAS#:2135-17-3 |
| Literature: WO2012/11106 A1, ; |
CAS#:2607-06-9
CAS#:28416-82-2| HS Code | 2937229000 |
|---|
|
Veterinary drug residues in domestic and imported foods of animal origin in the Republic of Korea.
Food. Addit. Contam. Part. B. Surveill. 8 , 106-12, (2015) The Korean National Residue Programme comprises three different approaches for evaluating domestic and imported foods of animal origin: monitoring, surveillance/enforcement and an exploratory test pro... |
|
|
Lecithin based nanoemulsions: A comparative study of the influence of non-ionic surfactants and the cationic phytosphingosine on physicochemical behaviour and skin permeation.
Int. J. Pharm. 370(1-2) , 181-6, (2009) Charged drug delivery systems are interesting candidates for the delivery of drugs through skin. In the present study, it was possible to create negatively and positively charged oil/water nanoemulsio... |
|
|
Tympanoplasty graft preparation using ear drops containing polyethylene glycol, flumethasone and clioquinol.
J. Laryngol. Otol. 125(8) , 853-5, (2011) The aim of tympanoplasty graft preparation is to stiffen the fascia or perichondrium and thereby to optimise ease of manipulation. We report 39 cases utilising a novel technique in which the graft is ... |
| Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-16α-methyl- |
| 6a-Fluorodexamethasone |
| Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16α)- |
| (6α,11β,16α)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
| 6α-Fluorodexamethasone |
| 6α,9α-Difluoro-16α-methylprednisolone |
| Aniprime |
| Flumethasone |
| (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluor-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-on |
| Fluvet |
| EINECS 218-370-9 |
| flumetasone |
| 6α,9α-Difluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione |
| Flucorticin |
| Anaprime |
| (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one |
| MFCD00056464 |
| Flumethason |
| Cortexilar |
| 6a,9a-Difluoro-16a-methylprednisolone |
| Methagon |
| (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |