IDH1 Inhibitor 7-d2

Modify Date: 2024-04-11 18:12:16

IDH1 Inhibitor 7-d2 structure	Common Name	IDH1 Inhibitor 7-d2
	CAS Number	2135309-51-0	Molecular Weight	461.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₂D₂F₃N₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IDH1 Inhibitor 7-d2

IDH1 Inhibitor 7-d2 is the deuterium labeled IDH1 Inhibitor 7 (HY-150238). IDH1 Inhibitor 7 is an IDH1 inhibitor with an IC50 of less than 100 nM[1][2].

Name	IDH1 Inhibitor 7-d2

Description	IDH1 Inhibitor 7-d2 is the deuterium labeled IDH1 Inhibitor 7 (HY-150238). IDH1 Inhibitor 7 is an IDH1 inhibitor with an IC50 of less than 100 nM[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH)
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Lei Jang, et al. Compound having mutant idh inhibitory activity, preparation method and use thereof. Patent WO2017162133A1.

Molecular Formula	C₂₂H₂₂D₂F₃N₇O
Molecular Weight	461.48

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: IDH1 Inhibitor 7-d2
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