HS80

Modify Date: 2024-01-03 15:18:42

HS80 Structure
HS80 structure
Common Name HS80
CAS Number 2138838-57-8 Molecular Weight 338.47
Density N/A Boiling Point N/A
Molecular Formula C19H22N4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HS80


HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.

 Names

Name HS80

 HS80 Biological Activity

Description HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.
Related Catalog
Target

FASN[1]

In Vitro Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells[1].
References

[1]. Alwarawrah Y, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23(6):678-88.

 Chemical & Physical Properties

Molecular Formula C19H22N4S
Molecular Weight 338.47