Cefapirin

Modify Date: 2024-01-02 10:41:15

Cefapirin Structure
Cefapirin structure
Common Name Cefapirin
CAS Number 21593-23-7 Molecular Weight 423.46300
Density N/A Boiling Point N/A
Molecular Formula C17H17N3O6S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cefapirin


Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity[1][2][3].

 Names

Name cephapirin
Synonym More Synonyms

 Cefapirin Biological Activity

Description Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity[1][2][3].
Related Catalog
In Vitro Cephapirin (Cefapirin) inhibits Staphylococcus aureus by cephapirin concentrations of 0.09 to 12.5 mug/mL[2]. Cephapirin (Cefapirin) inhibits S. epidermidis, S. viridans, S. pyogenes, and Diplococcus pneumonia isolates by less than 1 mug/mL[2].
In Vivo Cephapirin (Cefapirin) (200 mg; i.m.;cows) is effective for cows infected with S. aureus[3].
References

[1]. Bran JL, et al. Clinical and in vitro evaluation of cephapirin, a new cephalosporin antibiotic. Antimicrob Agents Chemother. 1972 Jan;1(1):35-40.

[2]. Axelrod J, et, al. Cephapirin: in vitro antibacterial spectrum. Appl Microbiol. 1971 Nov;22(5):904-8.

[3]. Roy JP, et, al. Efficacy of a 5-day extended therapy program during lactation with cephapirin sodium in dairy cows chronically infected with Staphylococcus aureus. Can Vet J. 2009 Dec;50(12):1257-62.

 Chemical & Physical Properties

Molecular Formula C17H17N3O6S2
Molecular Weight 423.46300
Exact Mass 423.05600
PSA 179.99000
LogP 1.25360
Vapour Pressure 6.98E-26mmHg at 25°C

 Synonyms

(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefapirin
Cefapirinum
Cefapirina
Cephapirine
7-(2-(4-pyridylthio)acetamido)cephalosporanic acid
Cefapirine
Cefaprin sodium
CEPR
Cefaprin
Cefa
(6R)-3-acetoxymethyl-8-oxo-7t-(2-pyridin-4-ylsulfanyl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid