PD 174265

Modify Date: 2024-01-29 14:15:24

PD 174265 Structure
PD 174265 structure
Common Name PD 174265
CAS Number 216163-53-0 Molecular Weight 371.23100
Density N/A Boiling Point N/A
Molecular Formula C17H15BrN4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PD 174265


PD 174265 is a potent, cell-permeable, reversible, and selective inhibitor of EGFR with an IC50 of 450 pM[1].

 Names

Name 4-N-(3-bromophenyl)-6-N-but-1-en-2-ylquinazoline-4,6-diamine

 Chemical & Physical Properties

Molecular Formula C17H15BrN4O
Molecular Weight 371.23100
Exact Mass 370.04300
PSA 66.91000
LogP 4.63040

 Synthetic Route

~47%

PD 174265 Structure

PD 174265

CAS#:216163-53-0

Literature: Warner-Lambert Company Patent: US6344459 B1, 2002 ; Location in patent: Page column 61-62 ; US 6344459 B1

 Precursor & DownStream

Precursor  2

DownStream  0

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