SHIP 2a

Modify Date: 2024-01-13 21:47:14

SHIP 2a Structure
SHIP 2a structure
Common Name SHIP 2a
CAS Number 2165706-30-7 Molecular Weight 184.22
Density N/A Boiling Point N/A
Molecular Formula C7H8N2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SHIP 2a


Cystathionine-γ-lyase-IN-1 is a selective cystathionine γ-lyase (CSE) enzyme inhibitor with an IC50 of 6.3 μM[1].

 Names

Name Cystathionine-γ-lyase-IN-1

 SHIP 2a Biological Activity

Description Cystathionine-γ-lyase-IN-1 is a selective cystathionine γ-lyase (CSE) enzyme inhibitor with an IC50 of 6.3 μM[1].
Related Catalog
In Vitro Cystathionine-γ-lyase-IN-1 (comp 2a) completely abrogates L-cysteine-induced vasorelaxation at a concentration of 100 μM[1]. Cystathionine-γ-lyase-IN-1 (100 μM; 30 minutes) significantly inhibits the increased H2S production stimulated by L-Cys at a lower dose in mouse aorta homogenates[1]. Cystathionine-γ-lyase-IN-1 inhibits the enzyme completely, keeping the concentration of substrate unaffected[1].
References

[1]. Angela Corvino, et al. Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production. Sci Rep. 2016 Oct 6;6:34398.

 Chemical & Physical Properties

Molecular Formula C7H8N2O2S
Molecular Weight 184.22
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