BMS-986278

Modify Date: 2024-01-03 10:25:43

BMS-986278 Structure
BMS-986278 structure
Common Name BMS-986278
CAS Number 2170126-74-4 Molecular Weight 445.51
Density N/A Boiling Point N/A
Molecular Formula C22H31N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS-986278


BMS-986278 is a potent lysophosphatidic acid receptor 1 (LPA1) antagonist, with a human LPA1 Kb of 6.9 nM.

 Names

Name BMS-986278

 BMS-986278 Biological Activity

Description BMS-986278 is a potent lysophosphatidic acid receptor 1 (LPA1) antagonist, with a human LPA1 Kb of 6.9 nM.
Related Catalog
References

[1]. Cheng PTW, et al. Murphy BJ. Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases. J Med Chem. 2021 Nov 11;64(21):15549-15581.

 Chemical & Physical Properties

Molecular Formula C22H31N5O5
Molecular Weight 445.51
Storage condition 2-8°C