MAK683 hydrochloride

Modify Date: 2024-01-03 12:10:33

MAK683 hydrochloride structure	Common Name	MAK683 hydrochloride
	CAS Number	2170606-94-5	Molecular Weight	412.85
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₈ClFN₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MAK683 hydrochloride

MAK683 hydrochloride is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2].

Name	MAK683 hydrochloride

Description	MAK683 hydrochloride is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
References	[1]. Chan, Ho Man, et al. TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF. US20160176882 A1. [2]. Huang D, et al. Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2. Chemphyschem. 2020 Feb 4;21(3):263-271.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

References

[1]. Chan, Ho Man, et al. TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF. US20160176882 A1.

[2]. Huang D, et al. Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2. Chemphyschem. 2020 Feb 4;21(3):263-271.