MAK683 hydrochloride

Modify Date: 2024-01-03 12:10:33

MAK683 hydrochloride Structure
MAK683 hydrochloride structure
Common Name MAK683 hydrochloride
CAS Number 2170606-94-5 Molecular Weight 412.85
Density N/A Boiling Point N/A
Molecular Formula C20H18ClFN6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MAK683 hydrochloride


MAK683 hydrochloride is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2].

 Names

Name MAK683 hydrochloride

 MAK683 hydrochloride Biological Activity

Description MAK683 hydrochloride is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2].
Related Catalog
References

[1]. Chan, Ho Man, et al. TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF. US20160176882 A1.

[2]. Huang D, et al. Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2. Chemphyschem. 2020 Feb 4;21(3):263-271.

 Chemical & Physical Properties

Molecular Formula C20H18ClFN6O
Molecular Weight 412.85
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