YKL-06-062
Modify Date: 2024-01-10 17:31:02
YKL-06-062 structure
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Common Name | YKL-06-062 | ||
|---|---|---|---|---|
| CAS Number | 2172617-16-0 | Molecular Weight | 525.69 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H39N7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of YKL-06-062YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM, respectively. YKL-06-062 is the structural analog of YKL-06-062[1]. |
| Name | YKL-06-062 |
|---|
| Description | YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM, respectively. YKL-06-062 is the structural analog of YKL-06-062[1]. |
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| In Vitro | YKL 06-062 (0.0004-16 μM; 3 hours) increases MITF mRNA expression in a dose-dependent manner[1]. RT-PCR[1] Cell Line: Human melanocyte cells, UACC62 melanoma cells Concentration: 0.0004 μM, 0.004 μM, 0.04 μM, 0.4 μM, 4 μM,8 μM,16 μM Incubation Time: 3 hours Result: Unregulated MITF mRNA expression. |
| References |
| Molecular Formula | C31H39N7O |
|---|---|
| Molecular Weight | 525.69 |