Metapramine
Modify Date: 2024-01-11 06:15:27
Metapramine structure
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Common Name | Metapramine | ||
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| CAS Number | 21730-16-5 | Molecular Weight | 238.32800 | |
| Density | 1.12g/cm3 | Boiling Point | 350.8ºC at 760mmHg | |
| Molecular Formula | C16H18N2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 140.7ºC | |
Use of MetapramineMetapramine (19560 RP) is an antidepressant agent, belonging to the class of tricyclic compounds[1]. Metapramine inhibits norepinephrine reuptake, without affecting the reuptake of serotonin or dopamine[1] [2] [3]. Metapramine is a low-affinity antagonist of the N-methyl-D-aspartic acid (NMDA) receptor complex channel[4]. |
| Name | N,11-dimethyl-5,6-dihydrobenzo[b][1]benzazepin-5-amine |
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| Synonym | More Synonyms |
| Description | Metapramine (19560 RP) is an antidepressant agent, belonging to the class of tricyclic compounds[1]. Metapramine inhibits norepinephrine reuptake, without affecting the reuptake of serotonin or dopamine[1] [2] [3]. Metapramine is a low-affinity antagonist of the N-methyl-D-aspartic acid (NMDA) receptor complex channel[4]. |
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| Related Catalog | |
| Target |
NMDA receptor complex channel[4] |
| In Vivo | Metapramine (19560 RP) (0-20 mg/kg; i.p.) shows analgesic effects in mice[5]. Animal Model: Male Swiss albino mice[5] Dosage: 0-20 mg/kg Administration: Intraperitoneal injection Result: Increased jump latency, threshold voltage, reduction in writhes, and tail flick latency in a dose-dependent manner. |
| References |
| Density | 1.12g/cm3 |
|---|---|
| Boiling Point | 350.8ºC at 760mmHg |
| Molecular Formula | C16H18N2 |
| Molecular Weight | 238.32800 |
| Flash Point | 140.7ºC |
| Exact Mass | 238.14700 |
| PSA | 15.27000 |
| LogP | 3.72700 |
| Vapour Pressure | 4.27E-05mmHg at 25°C |
| Index of Refraction | 1.633 |
| HS Code | 2933990090 |
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| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Metapramine |
| Metapramina |