TLR7/8/9-IN-1

Modify Date: 2024-01-11 05:18:40

TLR7/8/9-IN-1 Structure
TLR7/8/9-IN-1 structure
Common Name TLR7/8/9-IN-1
CAS Number 2180127-82-4 Molecular Weight 435.61
Density N/A Boiling Point N/A
Molecular Formula C27H37N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TLR7/8/9-IN-1


TLR7/8/9-IN-1 is a potent and orally bioavailable small molecule antagonist (IC50 = 43 nM) of Toll-like receptors 7/8/9 (TLR7/8/9).

 Names

Name BMS-615

 TLR7/8/9-IN-1 Biological Activity

Description TLR7/8/9-IN-1 is a potent and orally bioavailable small molecule antagonist (IC50 = 43 nM) of Toll-like receptors 7/8/9 (TLR7/8/9).
Related Catalog
References

[1]. Mussari CP, et al. Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9). ACS Med Chem Lett. 2020 Jul 29;11(9):1751-1758.

 Chemical & Physical Properties

Molecular Formula C27H37N3O2
Molecular Weight 435.61
Storage condition 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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