Thiorphan-d5

Modify Date: 2024-04-07 13:48:29

Thiorphan-d5 Structure
Thiorphan-d5 structure
Common Name Thiorphan-d5
CAS Number 2183240-70-0 Molecular Weight 258.35
Density 1.2±0.1 g/cm3 Boiling Point 524.0±50.0 °C at 760 mmHg
Molecular Formula C12H10D5NO3S Melting Point N/A
MSDS N/A Flash Point 270.7±30.1 °C

 Use of Thiorphan-d5


Thiorphan-d5 is deuterium labeled Thiorphan.

 Names

Name Thiorphan-d5
Synonym More Synonyms

 Thiorphan-d5 Biological Activity

Description Thiorphan-d5 is deuterium labeled Thiorphan.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 524.0±50.0 °C at 760 mmHg
Molecular Formula C12H10D5NO3S
Molecular Weight 258.35
Flash Point 270.7±30.1 °C
Exact Mass 258.108643
LogP 1.37
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.577

 Synonyms

THIORPHAN-D5
MFCD00058435
Glycine, N-[3-mercapto-1-oxo-2-(phenyl-d5-methyl)propyl]-
N-[3-(2H5)Phenyl-2-(sulfanylmethyl)propanoyl]glycine