Apremilast-d5
Modify Date: 2024-01-02 04:02:20
Apremilast-d5 structure
|
Common Name | Apremilast-d5 | ||
|---|---|---|---|---|
| CAS Number | 1258597-47-5 | Molecular Weight | 465.53100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H19D5N2O7S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Apremilast-d5Apremilast D5 (CC-10004 D5) is a deuterium labeled Apremilast. Apremilast is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1]. |
| Name | (S)-N-(2-(2-(methylsulfonyl)-1-(3-(ethoxy-d5)-4-(methoxy)phenyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide |
|---|---|
| Synonym | More Synonyms |
| Description | Apremilast D5 (CC-10004 D5) is a deuterium labeled Apremilast. Apremilast is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
PDE4 TNF-α |
| References |
| Molecular Formula | C22H19D5N2O7S |
|---|---|
| Molecular Weight | 465.53100 |
| Exact Mass | 465.16200 |
| PSA | 127.46000 |
| LogP | 3.52590 |
| Apremilast D5 |
| Apremilast-d5 |