2750534-79-1

2750534-79-1 structure

2750534-79-1 structure

Name: Milnacipran-d5 hydrochloride
Chemical Name: Milnacipran-d5 hydrochloride
CAS Number: 2750534-79-1
Molecular Formula: C₁₅H₁₈D₅ClN₂O
Molecular Weight: 287.84
Catalog: Signaling Pathways Neuronal Signaling Serotonin Transporter
Create Date: 2022-06-30 18:34:14
Modify Date: 2024-01-07 10:11:45
Milnacipran-d5 (hydrochloride) is deuterium labeled Milnacipran (hydrochloride).

Name	Milnacipran-d5 hydrochloride

Description	Milnacipran-d5 (hydrochloride) is deuterium labeled Milnacipran (hydrochloride).
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Moret C, et al. Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug. Neuropharmacology. 1985 Dec;24(12):1211-9. [3]. Briley M, et al. Preclinical pharmacology of milnacipran. Int Clin Psychopharmacol. 1996 Sep;11 Suppl 4:9-14.

Molecular Formula	C₁₅H₁₈D₅ClN₂O
Molecular Weight	287.84