3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

Modify Date: 2024-01-02 16:04:53

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone structure	Common Name	3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
	CAS Number	22246-18-0	Molecular Weight	163.173
	Density	1.3±0.1 g/cm3	Boiling Point	403.7±45.0 °C at 760 mmHg
	Molecular Formula	C₉H₉NO₂	Melting Point	233-237 °C
	MSDS	Chinese USA	Flash Point	198.0±28.7 °C
	Symbol	GHS07	Signal Word	Warning

Use of 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].

Name	7-hydroxy-3,4-dihydro-1H-quinolin-2-one
Synonym	More Synonyms

Description	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	IC50: 183 μM (MAO-A)[1]
In Vitro	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].
References	[1]. Meiring L, et al. Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5498-502.

Density	1.3±0.1 g/cm3
Boiling Point	403.7±45.0 °C at 760 mmHg
Melting Point	233-237 °C
Molecular Formula	C₉H₉NO₂
Molecular Weight	163.173
Flash Point	198.0±28.7 °C
Exact Mass	163.063324
PSA	49.33000
LogP	0.99
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.604

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H317
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xi: Irritant;Xn: Harmful;
Risk Phrases	R22;R43
Safety Phrases	S36/37
RIDADR	NONH for all modes of transport
HS Code	2933499090

Precursor 8
CAS#:21261-76-7 3-Chloro-N-(3-m... CAS#:50297-40-0 CHEMBRDG-BB 6018839 CAS#:536-90-3 3-anisidine CAS#:625-36-5 3-Chloropropano...
CAS#:591-27-5 3-Aminophenol CAS#:7403-75-0 N-(4-hydroxy-2-... CAS#:22246-17-9 7-Methoxy-3,4-d... CAS#:103986-96-5 3-(4-methoxy-2-...
DownStream 8
CAS#:58196-33-1 7-Hydroxy-1,2,3... CAS#:129722-12-9 Aripiprazole CAS#:129722-34-5 7-(4-Brombutoxy... CAS#:120004-79-7 7-(4-Chlorobuto...
CAS#:1194459-28-3 6-Bromo-7-hydro... CAS#:71130-68-2 1-Ethyl-1,2,3,4... CAS#:952308-47-3 7-(4-iodobutoxy... CAS#:58022-96-1 7-(3-chloroprop...

HS Code	2933790090
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

2,7-quinolinediol, 3,4-dihydro-

3,4-Dihydro-7-hydroxycarbostyril

MFCD06410891

2(1H)-Quinolinone, 3,4-dihydro-7-hydroxy-

7-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline

7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

7-Hydroxy-3,4-dihydro-quinolin-2-one

7-Hydroxy-3,4-dihydrochinolin-2(1H)-on

7-hydroxy-3,4-dihydroquinolin-2(1H)-one

7-hydroxy-3,4-dihydro-2-quinolinone

7-Hydroxy-3,4-dihydro carbostyril

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

7-hydroxy-3,4-dihydro-2(1H)quinolinone

Brexpiprazole Impurity 5

Aripiprazole - Impurity A

7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Price: ￥108.0/25g ￥288.0/100g
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3,4-Dihydro-7-hydroxycarbostyril
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 7-hydroxy-3,4-dihydro-1H-quinolin-2-one
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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3,4-Dihydro-7-hydroxy-2(1H)-quinolinone suppliers

Price: ￥550/10 mM * 1 mL in DMSO

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