Mal-PEG24-NHS ester

Modify Date: 2024-01-11 16:48:48

Mal-PEG24-NHS ester Structure
Mal-PEG24-NHS ester structure
Common Name Mal-PEG24-NHS ester
CAS Number 2226733-37-3 Molecular Weight 381.34
Density N/A Boiling Point N/A
Molecular Formula C16H19N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG24-NHS ester


Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-PEG24-NHS ester

 Mal-PEG24-NHS ester Biological Activity

Description Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C16H19N3O8
Molecular Weight 381.34
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