Methyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate

Modify Date: 2024-01-10 09:10:26

Methyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate structure	Common Name	Methyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate
	CAS Number	2228857-35-8	Molecular Weight	280.31
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₂₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Methyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate

Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Hydroxy-PEG4-C2-methyl ester

Description	Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₂H₂₄O₇
Molecular Weight	280.31