Avizakimab

Modify Date: 2024-04-06 17:54:21

Avizakimab Structure
Avizakimab structure
Common Name Avizakimab
CAS Number 2229685-51-0 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Avizakimab


Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21[1].

 Names

Name Avizakimab

 Avizakimab Biological Activity

Description Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21[1].
Related Catalog
In Vitro Avizakimab (BOS161721) 可阻止 IL-21 与 IL-21 受体 (IL-21R) 结合,并抑制生物活性[1]。 Avizakimab 可抑制 IL-21 诱导的下游信号传导、浆细胞分化和自然杀伤细胞激活,并抑制抗体对匙孔戚血蓝蛋白 (keyhole limpet hemocyanin; KLH) 抗原的反应[1]。
References

[1]. Hussaini A, et al. A Double-Blind, Phase I, Single Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of BOS161721 in Healthy Subjects. Clin Transl Sci. 2020 Mar;13(2):337-344.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties