ZL0590

Modify Date: 2024-01-10 08:33:12

ZL0590 Structure
ZL0590 structure
Common Name ZL0590
CAS Number 2230496-99-6 Molecular Weight 512.55
Density N/A Boiling Point N/A
Molecular Formula C23H27F3N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ZL0590


ZL0590 is a potent, orally active BRD4 BD1-selective inhibitor with an IC50 of 90 nM for human BRD4 BD1. ZL0590 exhibits significant anti-inflammatory activities[1].

 Names

Name ZL0590

 ZL0590 Biological Activity

Description ZL0590 is a potent, orally active BRD4 BD1-selective inhibitor with an IC50 of 90 nM for human BRD4 BD1. ZL0590 exhibits significant anti-inflammatory activities[1].
Related Catalog
Target

IC50: 90 nM (human BRD4 BD1)[1]

References

[1]. Liu Z, et al. Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site. J Med Chem. 2022;65(3):2388-2408.

 Chemical & Physical Properties

Molecular Formula C23H27F3N4O4S
Molecular Weight 512.55