MT-802

Modify Date: 2024-01-13 19:42:30

MT-802 structure	Common Name	MT-802
	CAS Number	2231744-29-7	Molecular Weight	787.82
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₁H₄₁N₉O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MT-802

MT-802 is a potent BTK degrader based on PROTAC technology, with a DC50 of 1 nM. MT-802 has potential to treat C481S mutant chronic lymphocytic leukemia (CLL)[1].

Name	MT-802

Description	MT-802 is a potent BTK degrader based on PROTAC technology, with a DC50 of 1 nM. MT-802 has potential to treat C481S mutant chronic lymphocytic leukemia (CLL)[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk Signaling Pathways >> PROTAC >> PROTAC
Target	DC50: 1 nM (BTK)[1].
In Vitro	MT-802 degrades BTK with a DC50 of 9.1 nM with maximal degradation being observed by 250 nM[1].
References	[1]. Buhimschi AD, et al. Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase Using PROTAC-Mediated Degradation. Biochemistry. 2018 Jul 3;57(26):3564-3575.

Molecular Formula	C₄₁H₄₁N₉O₈
Molecular Weight	787.82
Storage condition	-20°C

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MT-802
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: MT-802
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: MT-802
Price: $700.0/100mg $1200.0/250mg $2500.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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