Keap1-Nrf2-IN-1
Modify Date: 2024-01-11 16:34:14
Keap1-Nrf2-IN-1 structure
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Common Name | Keap1-Nrf2-IN-1 | ||
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| CAS Number | 2232112-72-8 | Molecular Weight | 484.52 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H24N2O7S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Keap1-Nrf2-IN-1Keap1–Nrf2 IN-1 (compound35) is a Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 (Keap1-Nrf2) protein-protein interaction inhibitor, and with an IC50 of 43 nM for Keap1 protein. Keap1–Nrf2 IN-1 (compound35) activates Nrf2-regulated cytoprotective response and antagonizes acetaminophen-induced liver injury both in cellular and in vivo models[1]. |
| Name | Keap1–Nrf2-IN-1 |
|---|
| Description | Keap1–Nrf2 IN-1 (compound35) is a Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 (Keap1-Nrf2) protein-protein interaction inhibitor, and with an IC50 of 43 nM for Keap1 protein. Keap1–Nrf2 IN-1 (compound35) activates Nrf2-regulated cytoprotective response and antagonizes acetaminophen-induced liver injury both in cellular and in vivo models[1]. |
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| Related Catalog | |
| Target |
IC50: 43 nM (Keap1 protein)[1] |
| References |
| Molecular Formula | C24H24N2O7S |
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| Molecular Weight | 484.52 |